FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Liang Howard
2. Issuer Name and Ticker or Trading Symbol

BeiGene, Ltd. [ BGNE ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
CFO & Chief Strategy Officer
(Last)          (First)          (Middle)

C/O MOURANT OZANNES CORPORATE SERVICES, 94 SOLARIS AVENUE
3. Date of Earliest Transaction (MM/DD/YYYY)

3/16/2018
(Street)

CAMANA BAY, GRAND CAYMAN, E9 KY1-1108
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
American Depositary Shares   (1) 3/16/2018     M    10872   A $6.5   (2) 15872   D    
American Depositary Shares   (1) 3/16/2018     S (3)    1000   D $154.95   14872   D    
American Depositary Shares   (1) 3/16/2018     S (3)    2208   D $156.7458   (4) 12664   D    
American Depositary Shares   (1) 3/16/2018     S (3)    7264   D $157.4105   (5) 5400   D    
Amerian Depositary Shares   (1) 3/16/2018     S (3)    400   D $157.9775   (6) 5000   D    
American Depositary Shares   (1) 3/19/2018     M    24128   A $6.5   (2) 29128   D    
American Depositary Shares   (1) 3/19/2018     S (3)    500   D $158.448   (7) 28628   D    
American Depositary Shares   (1) 3/19/2018     S (3)    5200   D $159.6234   (8) 23428   D    
American Depositary Shares   (1) 3/19/2018     S (3)    9618   D $160.6001   (9) 13810   D    
American Depositary Shares   (1) 3/19/2018     S (3)    3141   D $161.6239   (10) 10669   D    
American Depositary Shares   (1) 3/19/2018     S (3)    5133   D $162.7864   (11) 5536   D    
American Depositary Shares   (1) 3/19/2018     S (3)    4636   D $163.4818   (12) 900   D    
American Depositary Shares   (1) 3/19/2018     S (3)    900   D $164.3589   (13) 0   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   $0.5   (14) 3/16/2018     M         141336      (15) 7/1/2025   Ordinary Shares   141336   $0   4758664   D    
Share Option (Right to Buy)   $0.5   (14) 3/19/2018     M         313664      (15) 7/1/2025   Ordinary Shares   313664   $0   4445000   D    

Explanation of Responses:
(1)  Each American Depositary Share ("ADS") represents 13 Ordinary Shares.
(2)  The exercise price is represented in ADSs.
(3)  The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.
(4)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $155.95 to $156.94, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(5)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $156.95 to $157.93, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(6)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $157.97 to $157.98, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(7)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $158.04 to $158.86, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(8)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $159.06 to $160.05, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(9)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $160.07 to $161.05, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(10)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $161.13 to $162.05, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(11)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $162.15 to $163.13, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(12)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $163.16 to $164.15, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(13)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $164.16 to $165.03, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price.
(14)  The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.
(15)  These securities vest over a four-year period as follows: 25% on July 15, 2016, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon a sale event or certain termination events.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Liang Howard
C/O MOURANT OZANNES CORPORATE SERVICES
94 SOLARIS AVENUE
CAMANA BAY, GRAND CAYMAN, E9 KY1-1108


CFO & Chief Strategy Officer

Signatures
/s/ Scott A. Samuels, as Attorney-in-Fact 3/20/2018
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.